Statin Drug Costs: Zypitamag (The $35 Solution)

By Amy Allen December 05, 2025
Statin Drug Costs: Zypitamag (The $35 Solution)
Medical Disclaimer

The content provided in this article is for informational purposes only and does not constitute medical advice. Always consult your physician or a qualified healthcare provider regarding any medical condition or changes to your medication regimen.

In This Article:

  • The High Cost of Livalo (Pitavastatin)
  • The Chemistry: Magnesium vs. Calcium (Group 2 Elements)
  • Valence Electrons & Reactivity
  • The Math: 12 Months of Zypitamag vs. 2 Months of Livalo
  • How to Order via Marley Drug

Managing cholesterol shouldn't require taking out a loan. For many, the statin Livalo (pitavastatin) is a preferred medication due to its unique metabolic profile, but the brand-name price tag can be a shock to the system—even with insurance.

If you are a maker or engineer, you know that finding an efficient "workaround" is part of the lifestyle. In the pharmaceutical world, that workaround is Zypitamag. It is a brand-name pitavastatin option that bypasses the exorbitant pricing of Livalo. But how can they be different yet the same? The answer lies in the Periodic Table.


The Pitavastatin Problem

Pitavastatin is often prescribed because it has fewer drug-drug interactions compared to other statins. However, because Livalo has historically held tight patent protection, generic options have been limited, driving prices up. Many patients find themselves in the "donut hole" where a 30-day supply can cost upwards of hundreds of dollars.


The Chemistry: Mg vs. Ca

To understand why Zypitamag is a viable alternative to Livalo, we have to look at the molecular structure. Livalo is pitavastatin calcium. Zypitamag is pitavastatin magnesium.

Why does this substitution work? If you look at the Periodic Table of Elements, you will find both Magnesium (Mg) and Calcium (Ca) residing in Group 2: The Alkaline Earth Metals.

Periodic Table: Group 2
4 Be Beryllium
Zypitamag

12 Mg

Magnesium
Valence Electrons: 2
Livalo

20 Ca

Calcium
Valence Electrons: 2
38 Sr Strontium

Valence Electrons & Reactivity

In chemistry, the column (Group) an element belongs to is the primary indicator of its behavior.

  • Same Column: Elements in the same vertical column typically have the same number of valence electrons (electrons in the outermost shell).
  • The Result: Because both Mg and Ca have 2 valence electrons, they exhibit similar reactivity and bonding properties.

The "Maker" Takeaway: Think of the Pitavastatin molecule as the payload, and the salt (Mg or Ca) as the delivery stabilizer. Because Magnesium and Calcium are chemically analogous "cousins" in the Alkaline Earth Metals group, the manufacturers of Zypitamag were able to create a stable, effective alternative salt that bypasses the specific patent on the Calcium salt.


The Cost Breakdown: Marley Drug

The most efficient way to access Zypitamag is through Marley Drug, a direct-to-consumer pharmacy. Here is the math:

The Zypitamag Deal

~$35 / month

Through Marley Drug's cash price program.

  • Free Shipping
  • Order 3, 6, or 12-month supplies
The Comparison

The ROI is massive.

At current retail prices, 12 months of Zypitamag costs roughly the same as just 2 months of Livalo (depending on your local pharmacy's cash price).

By switching salts (from Ca to Mg), you are essentially getting 10 months of medication for free compared to the brand-name Livalo price point.


How to Make the Switch

You cannot simply swap medicines at the pharmacy counter; this requires a new prescription.

  1. Consult Your Doctor
    Ask your physician if switching from Livalo (pitavastatin calcium) to Zypitamag (pitavastatin magnesium) is appropriate.
  2. Request the Specific Script
    Ask your doctor to prescribe "Zypitamag" specifically.
  3. Send to Marley Drug
    Have the doctor e-scribe, fax, or call the prescription into Marley Drug.

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